Findings show promise for new anti-inflammatory drugs and treatments for autoimmune diseases
New research shows a group of enzymes may have a critical role in how immune cells are activated and then migrate to certain sites in the body – findings that could improve our understanding of inflammation and potentially lead to new treatments. In a recent study, researchers explored a particular family of enzymes called neuraminidases. "We…
Politicians have to stop creating impediments to access
By Nigel Rawson and John Adams Macdonald-Laurier Institute On April 14, 2022, Health Minister Jean-Yves Duclos announced the federal government’s decision to cancel most of its plan for the Patented Medicine Prices Review Board (PMPRB) to regulate significantly lower prices for new medicines in Canada – a mess created five years ago by then Health…
Research points the way to better tests and potential new treatments for pain management
Researchers have uncovered signature metabolites – much like fingerprints in the blood – linked to the cognitive dysfunction and impaired motor skills associated with medical cannabis treatment. The work could lead to better roadside blood tests for impairment, and could also point the way toward supplements or strains of medical cannabis that reduce impairment while…
Treatment acts like a Band-Aid for mutations, allowing the body to rebuild muscle tissue
Up to 45 per cent of patients with the most common inherited neuromuscular disease could benefit from a new “cocktail” drug being developed at the University of Alberta, according to research published this week in the Proceedings of the National Academy of Sciences. The drug could provide an effective and economical treatment to lessen symptoms for the six of…
Mushrooms show long-term benefits in those who suffer from treatment-resistant depression
Regardless of where one stands on legalizing psychedelics for mental-health treatment, Canada is late to the party when it comes to relaxing federal regulations. And given the disturbing rise (and costs of treating) trauma, depression and other mental health disorders worldwide, we better speed up. University researchers, consumers, investors and private-sector companies aren’t waiting for…
Understanding drugs and viruses key to being ready for the next pandemic
Understanding exactly how antiviral drugs interact with viruses at a molecular level will be key to developing the broad-spectrum therapies needed to battle against the SARS-CoV-2 pandemic and get ready to fight the next one, according to a newly published paper in the The Journal of Biological Chemistry. The paper reveals the inner workings of the…
Drug users are going to keep using, so a better route to saving lives is to ensure drugs are clean and safe
We’re supposed to be merry and bright as we approach the holidays and the new year. This year, there are many reasons to be less cheerful and festive. We’ve managed to make it through floods, fires and heat domes, but the pandemic persists with the Omicron mutation, inflation threatens our economy and the big, ugly…
Calls for rigorous research to determine if short-term medical use in children is safe
Pediatric researchers are calling for more rigorous research into the possible link between short-term opioid use for pain management in childhood and opioid use disorder later in life. The University of Alberta team reviewed the results of 21 previous studies but found no definitive answer to the question, according to a new study published this week in…
Alberta invests $55.1M to taking vaccines, antiviral drugs from discovery to manufacturing
Alberta is building a better pipeline, but this one’s not for oil and gas products – it’s for vaccines and therapeutic drugs to fight viral diseases. The province announced a $55.1-million grant on Wednesday for University of Alberta research on ways to prevent and treat COVID-19, including $15 million for vaccine projects and $10 million for studies…
The well-being of patients is at risk
By Krystle Wittevrongel and Maria Lily Shaw Montreal Economic Institute A highly-contested drug-price reform is set to come into effect in Canada in January 2022. Critics of the major overhaul, including patient groups, doctors, and academics, are hopeful that the new federal cabinet will take their concerns to heart and rather than stifle pharmaceutical innovation,…